Preclinical Remodeling of Human Prostate Cancer through the PTEN/AKT Pathway

Knowledge gained from the identification of genetic and epigenetic alterations that contribute to the progression of prostate cancer in humans is now being implemented in the development of functionally relevant translational models. GEM (genetically modified mouse) models are being developed to inc...

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Bibliographic Details
Main Authors: De Velasco, Marco A., Uemura, Hirotsugu
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290809/