B Cell Responses to CpG Correlate with CXCL16 Expression Levels in Common Variable Immunodeficiency

Broad Toll-like receptor 9 (TLR9) signalling defects after CpG in vitro stimulation have been described in common variable immunodeficiency (CVID). CXCL16, a surface receptor, was recently shown to influence cell responses to CpG. We evaluated the expression and function of CXCL16 on B cells from he...

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Bibliographic Details
Main Authors: Lougaris, Vassilios, Baronio, Manuela, Vitali, Massimiliano, Tampella, Giacomo, Soresina, Annarosa, Badolato, Raffaele, Plebani, Alessandro
Format: Online
Language:English
Published: The Scientific World Journal 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289902/