Antigen depot is not required for alum adjuvanticity
Alum adjuvants have been in continuous clinical use for more than 80 yr. While the prevailing theory has been that depot formation and the associated slow release of antigen and/or inflammation are responsible for alum enhancement of antigen presentation and subsequent T- and B-cell responses, this...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Federation of American Societies for Experimental Biology
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289510/ |