A pathway-based association analysis model using common and rare variants

How various genetic effects in combination affect susceptibility to certain disease states continues to be a major area of methodological research. Various rare variant models have been proposed, in response to a common failure to either identify or validate biologically driven causal genetic varian...

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Bibliographic Details
Main Authors: Cheng, Lu, Hu, Pingzhao, Sykes, Jenna, Pintilie, Melania, Liu, Geoffrey, Xu, Wei
Format: Online
Language:English
Published: BioMed Central 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287926/