Combining effects from rare and common genetic variants in an exome-wide association study of sequence data

Recent breakthroughs in next-generation sequencing technologies allow cost-effective methods for measuring a growing list of cellular properties, including DNA sequence and structural variation. Next-generation sequencing has the potential to revolutionize complex trait genetics by directly measurin...

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Bibliographic Details
Main Authors: Aschard, Hugues, Qiu, Weiliang, Pasaniuc, Bogdan, Zaitlen, Noah, Cho, Michael H, Carey, Vincent
Format: Online
Language:English
Published: BioMed Central 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287881/