Comparison of SNP-based and gene-based association studies in detecting rare variants using unrelated individuals

We compare the SNP-based and gene-based association studies using 697 unrelated individuals. The Benjamini-Hochberg procedure was applied to control the false discovery rate for all the multiple comparisons. We use a linear model for the single-nucleotide polymorphism (SNP) based association study....

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Bibliographic Details
Main Authors: Tong, Liping, Tayo, Bamidele, Yang, Jie, Cooper, Richard S
Format: Online
Language:English
Published: BioMed Central 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287878/