Pathway analysis for family data using nested random-effects models
Recently we proposed a novel two-step approach to test for pathway effects in disease progression. The goal of this approach is to study the joint effect of multiple single-nucleotide polymorphisms that belong to certain genes. By using random effects, our approach acknowledges the correlations with...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
BioMed Central
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287857/ |