A LASSO-based approach to analyzing rare variants in genetic association studies

Genetic markers with rare variants are spread out in the genome, making it necessary and difficult to consider them in genetic association studies. Consequently, wisely combining rare variants into “composite” markers may facilitate meaningful analyses. In this paper, we propose a novel approach of...

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Bibliographic Details
Main Authors: Brennan, Jennifer S, He, Yunxiao, Calixte, Rose, Nyirabahizi, Epiphanie, Jiang, Yuan, Zhang, Heping
Format: Online
Language:English
Published: BioMed Central 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287823/