DNA-guided assembly of biosynthetic pathways promotes improved catalytic efficiency

DNA-guided assembly of biosynthetic pathways promotes improved catalytic efficiency

Synthetic scaffolds that permit spatial and temporal organization of enzymes in living cells are a promising post-translational strategy for controlling the flow of information in both metabolic and signaling pathways. Here, we describe the use of plasmid DNA as a stable, robust and configurable sca...

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Bibliographic Details
Main Authors: Conrado, Robert J., Wu, Gabriel C., Boock, Jason T., Xu, Hansen, Chen, Susan Y., Lebar, Tina, Turnšek, Jernej, Tomšič, Nejc, Avbelj, Monika, Gaber, Rok, Koprivnjak, Tomaž, Mori, Jerneja, Glavnik, Vesna, Vovk, Irena, Benčina, Mojca, Hodnik, Vesna, Anderluh, Gregor, Dueber, John E., Jerala, Roman, DeLisa, Matthew P.
Format: Online
Language:English
Published: Oxford University Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287197/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287197/

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