RECQL5 cooperates with Topoisomerase II alpha in DNA decatenation and cell cycle progression

DNA decatenation mediated by Topoisomerase II is required to separate the interlinked sister chromatids post-replication. SGS1, a yeast homolog of the human RecQ family of helicases interacts with Topoisomerase II and plays a role in chromosome segregation, but this functional interaction has yet to...

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Bibliographic Details
Main Authors: Ramamoorthy, Mahesh, Tadokoro, Takashi, Rybanska, Ivana, Ghosh, Avik K., Wersto, Robert, May, Alfred, Kulikowicz, Tomasz, Sykora, Peter, Croteau, Deborah L., Bohr, Vilhelm A.
Format: Online
Language:English
Published: Oxford University Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287182/