Systemic Delivery of Oncolytic Viruses: Hopes and Hurdles

Despite recent advances in both surgery and chemoradiotherapy, mortality rates for advanced cancer remain high. There is a pressing need for novel therapeutic strategies; one option is systemic oncolytic viral therapy. Intravenous administration affords the opportunity to treat both the primary tumo...

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Bibliographic Details
Main Authors: Ferguson, Mark S., Lemoine, Nicholas R., Wang, Yaohe
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287020/