A Possible Contribution of Altered Cathepsin B Expression to the Development of Skin Sclerosis and Vasculopathy in Systemic Sclerosis

A Possible Contribution of Altered Cathepsin B Expression to the Development of Skin Sclerosis and Vasculopathy in Systemic Sclerosis

Cathepsin B (CTSB) is a proteolytic enzyme potentially modulating angiogenic processes and extracellular matrix remodeling. While matrix metalloproteinases are shown to be implicated in tissue fibrosis and vasculopathy associated with systemic sclerosis (SSc), the role of cathepsins in this disease...

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Bibliographic Details
Main Authors: Noda, Shinji, Asano, Yoshihide, Akamata, Kaname, Aozasa, Naohiko, Taniguchi, Takashi, Takahashi, Takehiro, Ichimura, Yohei, Toyama, Tetsuo, Sumida, Hayakazu, Yanaba, Koichi, Tada, Yayoi, Sugaya, Makoto, Kadono, Takafumi, Sato, Shinichi
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285678/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285678/

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