Superior Neuroprotective Efficacy of LAU-0901, a Novel Platelet-Activating Factor Antagonist, in Experimental Stroke

Platelet-activating factor (PAF) accumulates during cerebral ischemia, and inhibition of this process plays a critical role in neuronal survival. Recently, we demonstrated that LAU-0901, a novel PAF receptor antagonist, is neuroprotective in experimental stroke. We used magnetic resonance imaging in...

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Bibliographic Details
Main Authors: Belayev, Ludmila, Eady, Tiffany N., Khoutorova, Larissa, Atkins, Kristal D., Obenaus, Andre, Cordoba, Marta, Vaquero, Juan J., Alvarez-Builla, Julio, Bazan, Nicolas G.
Format: Online
Language:English
Published: Springer-Verlag 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284672/