Prostatic Metastasis of Pulmonary Large Cell Neuroendocrine Carcinoma

Lung cancer metastases to the prostate are uncommon, and are usually found incidentally during autopsy. This case report describes a 77-year-old man with a large cell neuroendocrine carcinoma (LCNEC) of the lung and metastases from this primary cancer in the prostate. During the follow-up after the...

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Bibliographic Details
Main Authors: Shimizu, Kumi, Goto, Taichiro, Maeshima, Arafumi, Oyamada, Yoshitaka, Kato, Ryoichi
Format: Online
Language:English
Published: Ivyspring International Publisher 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283836/
Description
Summary:Lung cancer metastases to the prostate are uncommon, and are usually found incidentally during autopsy. This case report describes a 77-year-old man with a large cell neuroendocrine carcinoma (LCNEC) of the lung and metastases from this primary cancer in the prostate. During the follow-up after the chemotherapy performed for pulmonary LCNEC, pelvic computed tomography revealed a prostatic tumor and prostatic needle biopsy was performed. Histologically, the tumor was identified as LCNEC, forming a tissue architecture closely resembling the previously diagnosed lung cancer. The tumor cells were immunohistochemically positive for thyroid transcription factor-1. These findings led to a diagnosis of prostatic metastasis of pulmonary LCNEC.