Approximating the double-cut-and-join distance between unsigned genomes

In this paper we study the problem of sorting unsigned genomes by double-cut-and-join operations, where genomes allow a mix of linear and circular chromosomes to be present. First, we formulate an equivalent optimization problem, called maximum cycle/path decomposition, which is aimed at finding a l...

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Bibliographic Details
Main Authors: Chen, Xin, Sun, Ruimin, Yu, Jiadong
Format: Online
Language:English
Published: BioMed Central 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283313/