Blockade of ERK Phosphorylation in the Nucleus Accumbens Inhibits the Expression of Cocaine-induced Behavioral Sensitization in Rats
Repeated administration of psychostimulants such as cocaine leads to the development of behavioral sensitization. Extracellular signal-Regulated Kinase (ERK), an enzyme important for long-term neuronal plasticity, has been implicated in such effects of these drugs. Although the nucleus accumbens (NA...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
The Korean Physiological Society and The Korean Society of Pharmacology
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282227/ |