Blockade of ERK Phosphorylation in the Nucleus Accumbens Inhibits the Expression of Cocaine-induced Behavioral Sensitization in Rats

Repeated administration of psychostimulants such as cocaine leads to the development of behavioral sensitization. Extracellular signal-Regulated Kinase (ERK), an enzyme important for long-term neuronal plasticity, has been implicated in such effects of these drugs. Although the nucleus accumbens (NA...

Full description

Bibliographic Details
Main Authors: Kim, Seungwoo, Shin, Joong-Keun, Yoon, Hyung Shin, Kim, Jeong-Hoon
Format: Online
Language:English
Published: The Korean Physiological Society and The Korean Society of Pharmacology 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282227/