A Modular Strategy to Prepare Multivalent Inhibitors of Prostate-Specific Membrane Antigen (PSMA)

A Modular Strategy to Prepare Multivalent Inhibitors of Prostate-Specific Membrane Antigen (PSMA)

We have developed a modular scaffold for preparing high-affinity, homo-multivalent inhibitors of the prostate-specific membrane antigen (PSMA) for imaging and therapy of prostate cancer (PCa). Our system contains a lysine-based (∝-, ε-) dialkyne residue for incorporating a PSMA binding Lys-Glu urea...

Full description

Bibliographic Details
Main Authors: Banerjee, Sangeeta Ray, Pullambhatla, Mrudula, Shallal, Hassan, Lisok, Ala, Mease, Ronnie C., Pomper, Martin G.
Format: Online
Language:English
Published: Impact Journals LLC 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282081/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282081/

Similar Items