MiRNA Genes Constitute New Targets for Microsatellite Instability in Colorectal Cancer

Mismatch repair-deficient colorectal cancers (CRC) display widespread instability at DNA microsatellite sequences (MSI). Although MSI has been reported to commonly occur at coding repeats, leading to alterations in the function of a number of genes encoding cancer-related proteins, nothing is known...

Full description

Bibliographic Details
Main Authors: El-Murr, Nizar, Abidi, Zoulira, Wanherdrick, Kristell, Svrcek, Magali, Gaub, Marie-Pierre, Fléjou, Jean-François, Hamelin, Richard, Duval, Alex, Lesuffleur, Thécla
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279428/