Direct inhibition of myosin II effectively blocks glioma invasion in the presence of multiple motogens

ETOC: Brain invasion by gliomas makes these tumors particularly malignant. In this paper, we demonstrate that these tumors need myosin II to drive this process and that the need for myosin II cannot be replaced by stimulating the upstream signal transduction cascades that are pathogenic in this dise...

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Bibliographic Details
Main Authors: Ivkovic, Sanja, Beadle, Christopher, Noticewala, Sonal, Massey, Susan C., Swanson, Kristin R., Toro, Laura N., Bresnick, Anne R., Canoll, Peter, Rosenfeld, Steven S.
Format: Online
Language:English
Published: The American Society for Cell Biology 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279383/