Genome-Wide Analysis of Nascent Transcription in Saccharomyces cerevisiae

The assessment of transcriptional regulation requires a genome-wide survey of active RNA polymerases. Thus, we combined the nuclear run-on assay, which labels and captures nascent transcripts, with high-throughput DNA sequencing to examine transcriptional activity in exponentially growing Saccharomy...

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Bibliographic Details
Main Authors: McKinlay, Anastasia, Araya, Carlos L., Fields, Stanley
Format: Online
Language:English
Published: Genetics Society of America 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276176/