Lamellar Granule Secretion Starts before the Establishment of Tight Junction Barrier for Paracellular Tracers in Mammalian Epidermis

Defects in epidermal barrier function and/or vesicular transport underlie severe skin diseases including ichthyosis and atopic dermatitis. Tight junctions (TJs) form a single layered network in simple epithelia. TJs are important for both barrier functions and vesicular transport. Epidermis is strat...

Full description

Bibliographic Details
Main Authors: Ishida-Yamamoto, Akemi, Kishibe, Mari, Murakami, Masamoto, Honma, Masaru, Takahashi, Hidetoshi, Iizuka, Hajime
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273471/