Sequence Heterogeneity in NS5A of Hepatitis C Virus Genotypes 2a and 2b and Clinical Outcome of Pegylated-Interferon/Ribavirin Therapy

Sequence Heterogeneity in NS5A of Hepatitis C Virus Genotypes 2a and 2b and Clinical Outcome of Pegylated-Interferon/Ribavirin Therapy

Pegylated-interferon plus ribavirin (PEG-IFN/RBV) therapy is a current standard treatment for chronic hepatitis C. We previously reported that the viral sequence heterogeneity of part of NS5A, referred to as the IFN/RBV resistance-determining region (IRRDR), and a mutation at position 70 of the core...

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Main Authors: El-Shamy, Ahmed, Shoji, Ikuo, Kim, Soo-Ryang, Ide, Yoshihiro, Imoto, Susumu, Deng, Lin, Yoon, Seitetsu, Fujisawa, Takashi, Tani, Satoshi, Yano, Yoshihiko, Seo, Yasushi, Azuma, Takeshi, Hotta, Hak
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271109/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271109/

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