Visualization and Quantitative Analysis of Reconstituted Tight Junctions Using Localization Microscopy

Tight Junctions (TJ) regulate paracellular permeability of tissue barriers. Claudins (Cld) form the backbone of TJ-strands. Pore-forming claudins determine the permeability for ions, whereas that for solutes and macromolecules is assumed to be crucially restricted by the strand morphology (i.e., den...

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Bibliographic Details
Main Authors: Kaufmann, Rainer, Piontek, Jörg, Grüll, Frederik, Kirchgessner, Manfred, Rossa, Jan, Wolburg, Hartwig, Blasig, Ingolf E., Cremer, Christoph
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271094/