Melanopsin Signaling in Mammalian Iris and Retina

Lower vertebrates have an intrinsically-photosensitive iris and thus a local pupillary light reflex (PLR). In contrast, it has been a dogma that the PLR in mammals generally requires neuronal circuitry connecting the eye and the brain. We report here that an intrinsic component of the PLR is actuall...

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Bibliographic Details
Main Authors: Xue, T., Do, M. T. H., Riccio, A., Jiang, Z., Hsieh, J., Wang, H. C., Merbs, S. L., Welsbie, D. S., Yoshioka, T., Weissgerber, P., Stolz, S., Flockerzi, V., Freichel, M., Simon, M. I., Clapham, D. E., Yau, K.-W.
Format: Online
Language:English
Published: 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270891/