Molecular Basis of Medullary Thyroid Carcinoma: The Role of RET Polymorphisms
Medullary thyroid carcinoma is a rare malignant tumor originating in parafollicular C cells. It accounts for 5 to 8% of all thyroid cancers. MTC develops in either sporadic (75%) or hereditary form (25%). Genetic and molecular studies have demonstrated the involvement of the RET proto-oncogene in he...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
Molecular Diversity Preservation International (MDPI)
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269683/ |