Calpains promote α2β1 integrin turnover in nonrecycling integrin pathway

Calpains promote α2β1 integrin turnover in nonrecycling integrin pathway

A novel virus- and integrin clustering–specific pathway diverts integrin from its normal endo/exocytic traffic to a nonrecycling degradative endosomal route. Clustering of α2β1 integrin causes redistribution of the integrin to perinuclear endosomes, leading to enhanced integrin turnover promoted by...

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Bibliographic Details
Main Authors: Rintanen, Nina, Karjalainen, Mikko, Alanko, Jonna, Paavolainen, Lassi, Mäki, Anita, Nissinen, Liisa, Lehkonen, Moona, Kallio, Katri, Cheng, R. Holland, Upla, Paula, Ivaska, Johanna, Marjomäki, Varpu
Format: Online
Language:English
Published: The American Society for Cell Biology 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268724/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268724/

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