Serpin Inhibition Mechanism: A Delicate Balance between Native Metastable State and Polymerization
The serpins (serine proteinase inhibitors) are structurally similar but functionally diverse proteins that fold into a conserved structure and employ a unique suicide substrate-like inhibitory mechanism. Serpins play absolutely critical role in the control of proteases involved in the inflammatory,...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
SAGE-Hindawi Access to Research
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268027/ |