Prolyl Oligopeptidase, Inositol Phosphate Signalling and Lithium Sensitivity
Inhibition of prolyl oligopeptidase (PO) elevates inositol phosphate (IP) signalling and reduces cell sensitivity to lithium (Li+). This review discusses recent evidence that shows PO acts via the multiple inositol polyphosphate phosphatase (MIPP) to regulate gene expression. As a consequence, PO in...
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| Format: | Online |
| Language: | English |
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Bentham Science Publishers
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267164/ |