EPITHELIAL NUCLEAR FACTOR-κB SIGNALING PROMOTES LUNG CARCINOGENESIS VIA RECRUITMENT OF REGULATORY T LYMPHOCYTES

The mechanisms by which chronic inflammatory lung diseases, particularly chronic obstructive pulmonary disease (COPD), confer enhanced risk for lung cancer are not well defined. To investigate whether nuclear factor (NF)-κB, a key mediator of immune and inflammatory responses, provides an interface...

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Main Authors: Zaynagetdinov, Rinat, Stathopoulos, Georgios T., Sherrill, Taylor P., Cheng, Dong-Sheng, McLoed, Allyson G., Ausborn, Jamie A., Polosukhin, Vasiliy V., Connelly, Linda, Zhou, Weisong, Fingleton, Barbara, Peebles, R. Stokes, Prince, Lawrence S., Yull, Fiona E., Blackwell, Timothy S.
Format: Online
Language:English
Published: 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266969/