cGMP Signaling, Phosphodiesterases and Major Depressive Disorder
Deficits in neuroplasticity are hypothesized to underlie the pathophysiology of major depressive disorder (MDD): the effectiveness of antidepressants is thought to be related to the normalization of disrupted synaptic transmission and neurogenesis. The cyclic adenosine monophosphate (cAMP) signaling...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
Bentham Science Publishers
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263465/ |