Role of Neurotrophins in Neuropathic Pain
Neurotrophins (NTs) belong to a family of structurally and functionally related proteins, they are the subsets of neurotrophic factors. Neurotrophins are responsible for diverse actions in the developing peripheral and central nervous systems. They are important regulators of neuronal function, affe...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Bentham Science Publishers
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263449/ |
| Summary: | Neurotrophins (NTs) belong to a family of structurally and functionally related proteins, they are the subsets of neurotrophic factors. Neurotrophins are responsible for diverse actions in the developing peripheral and central nervous systems. They are important regulators of neuronal function, affecting neuronal survival and growth. They are able to regulate cell death and survival in development as well as in pathophysiologic states. NTs and their receptors are expressed in areas of the brain that undergo plasticity, indicating that they are able to modulate synaptic plasticity. |
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