Ser7 Phosphorylation of the CTD Recruits the RPAP2 Ser5 Phosphatase to snRNA Genes
The carboxy-terminal domain (CTD) of the large subunit of RNA polymerase II (Pol II) comprises multiple heptapeptide repeats of the consensus Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. Reversible phosphorylation of Ser2, Ser5, and Ser7 during the transcription cycle mediates the sequential recruitment of t...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
Cell Press
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262128/ |