Cancer Surgery in the Elderly
The proportions both of elderly patients in the world and of elderly patients with cancer are both increasing. In the evaluation of these patients, physiologic age, and not chronologic age, should be carefully considered in the decision-making process prior to both cancer screening and cancer treatm...
| Main Authors: | , , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
The Scientific World Journal
2012
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259553/ |
| id |
pubmed-3259553 |
|---|---|
| recordtype |
oai_dc |
| spelling |
pubmed-32595532012-01-23 Cancer Surgery in the Elderly Kowdley, Gopal C. Merchant, Nishant Richardson, James P. Somerville, Justin Gorospe, Myriam Cunningham, Steven C. Review Article The proportions both of elderly patients in the world and of elderly patients with cancer are both increasing. In the evaluation of these patients, physiologic age, and not chronologic age, should be carefully considered in the decision-making process prior to both cancer screening and cancer treatment in an effort to avoid ageism. Many tools exist to help the practitioner determine the physiologic age of the patient, which allows for more appropriate and more individualized risk stratification, both in the pre- and postoperative periods as patients are evaluated for surgical treatments and monitored for surgical complications, respectively. During and after operations in the oncogeriatric populations, physiologic changes occuring that accompany aging include impaired stress response, increased senescence, and decreased immunity, all three of which impact the risk/benefit ratio associated with cancer surgery in the elderly. The Scientific World Journal 2012-01-03 /pmc/articles/PMC3259553/ /pubmed/22272172 http://dx.doi.org/10.1100/2012/303852 Text en Copyright © 2012 Gopal C. Kowdley et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Kowdley, Gopal C. Merchant, Nishant Richardson, James P. Somerville, Justin Gorospe, Myriam Cunningham, Steven C. |
| spellingShingle |
Kowdley, Gopal C. Merchant, Nishant Richardson, James P. Somerville, Justin Gorospe, Myriam Cunningham, Steven C. Cancer Surgery in the Elderly |
| author_facet |
Kowdley, Gopal C. Merchant, Nishant Richardson, James P. Somerville, Justin Gorospe, Myriam Cunningham, Steven C. |
| author_sort |
Kowdley, Gopal C. |
| title |
Cancer Surgery in the Elderly |
| title_short |
Cancer Surgery in the Elderly |
| title_full |
Cancer Surgery in the Elderly |
| title_fullStr |
Cancer Surgery in the Elderly |
| title_full_unstemmed |
Cancer Surgery in the Elderly |
| title_sort |
cancer surgery in the elderly |
| description |
The proportions both of elderly patients in the world and of elderly patients with cancer are both increasing. In the evaluation of these patients, physiologic age, and not chronologic age, should be carefully considered in the decision-making process prior to both cancer screening and cancer treatment in an effort to avoid ageism. Many tools exist to help the practitioner determine the physiologic age of the patient, which allows for more appropriate and more individualized risk stratification, both in the pre- and postoperative periods as patients are evaluated for surgical treatments and monitored for surgical complications, respectively. During and after operations in the oncogeriatric populations, physiologic changes occuring that accompany aging include impaired stress response, increased senescence, and decreased immunity, all three of which impact the risk/benefit ratio associated with cancer surgery in the elderly. |
| publisher |
The Scientific World Journal |
| publishDate |
2012 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259553/ |
| _version_ |
1611500314733576192 |