Chronic CaMKII inhibition blunts the cardiac contractile response to exercise training

Activation of the multifunctional Ca2+/calmodulin-dependent protein kinase II (CaMKII) plays a critical role modulating cardiac function in both health and disease. Here, we determined the effect of chronic CaMKII inhibition during an exercise training program in healthy mice. CaMKII was inhibited b...

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Bibliographic Details
Main Authors: Kaurstad, Guri, Alves, Marcia N., Kemi, Ole J., Rolim, Natale, Høydal, Morten A., Wisløff, Helene, Stølen, Tomas O., Wisløff, Ulrik
Format: Online
Language:English
Published: Springer-Verlag 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258410/