A mass spectrometry-guided genome mining approach for natural product peptidogenomics

Peptide natural products exhibit broad biological properties and are commonly produced by orthogonal ribosomal and nonribosomal pathways in prokaryotes and eukaryotes. To harvest this large and diverse resource of bioactive molecules, we introduce Natural Product Peptidogenomics (NPP), a new mass sp...

Full description

Bibliographic Details
Main Authors: Kersten, Roland D., Yang, Yu-Liang, Xu, Yuquan, Cimermancic, Peter, Nam, Sang-Jip, Fenical, William, Fischbach, Michael A., Moore, Bradley S., Dorrestein, Pieter C.
Format: Online
Language:English
Published: 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258187/