Regulation of exocytosis by the exocyst subunit Sec6 and the SM protein Sec1

The Sec6 subunit of the multisubunit exocyst tethering complex interacts with the Sec1/Munc18 protein Sec1 and with the t-SNARE Sec9. Assembly of the exocyst upon vesicle arrival at sites of secretion is proposed to release Sec9 for SNARE complex assembly and to recruit Sec1 for interaction with SNA...

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Bibliographic Details
Main Authors: Morgera, Francesca, Sallah, Margaret R., Dubuke, Michelle L., Gandhi, Pallavi, Brewer, Daniel N., Carr, Chavela M., Munson, Mary
Format: Online
Language:English
Published: The American Society for Cell Biology 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258177/