Folic Acid Food Fortification—Its History, Effect, Concerns, and Future Directions

Periconceptional intake of folic acid is known to reduce a woman’s risk of having an infant affected by a neural tube birth defect (NTD). National programs to mandate fortification of food with folic acid have reduced the prevalence of NTDs worldwide. Uncertainty surrounding possible unintended cons...

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Main Authors: Crider, Krista S., Bailey, Lynn B., Berry, Robert J.
Format: Online
Language:English
Published: MDPI 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257747/
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spelling pubmed-32577472012-01-17 Folic Acid Food Fortification—Its History, Effect, Concerns, and Future Directions Crider, Krista S. Bailey, Lynn B. Berry, Robert J. Review Periconceptional intake of folic acid is known to reduce a woman’s risk of having an infant affected by a neural tube birth defect (NTD). National programs to mandate fortification of food with folic acid have reduced the prevalence of NTDs worldwide. Uncertainty surrounding possible unintended consequences has led to concerns about higher folic acid intake and food fortification programs. This uncertainty emphasizes the need to continually monitor fortification programs for accurate measures of their effect and the ability to address concerns as they arise. This review highlights the history, effect, concerns, and future directions of folic acid food fortification programs. MDPI 2011-03-15 /pmc/articles/PMC3257747/ /pubmed/22254102 http://dx.doi.org/10.3390/nu3030370 Text en © 2011 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Crider, Krista S.
Bailey, Lynn B.
Berry, Robert J.
spellingShingle Crider, Krista S.
Bailey, Lynn B.
Berry, Robert J.
Folic Acid Food Fortification—Its History, Effect, Concerns, and Future Directions
author_facet Crider, Krista S.
Bailey, Lynn B.
Berry, Robert J.
author_sort Crider, Krista S.
title Folic Acid Food Fortification—Its History, Effect, Concerns, and Future Directions
title_short Folic Acid Food Fortification—Its History, Effect, Concerns, and Future Directions
title_full Folic Acid Food Fortification—Its History, Effect, Concerns, and Future Directions
title_fullStr Folic Acid Food Fortification—Its History, Effect, Concerns, and Future Directions
title_full_unstemmed Folic Acid Food Fortification—Its History, Effect, Concerns, and Future Directions
title_sort folic acid food fortification—its history, effect, concerns, and future directions
description Periconceptional intake of folic acid is known to reduce a woman’s risk of having an infant affected by a neural tube birth defect (NTD). National programs to mandate fortification of food with folic acid have reduced the prevalence of NTDs worldwide. Uncertainty surrounding possible unintended consequences has led to concerns about higher folic acid intake and food fortification programs. This uncertainty emphasizes the need to continually monitor fortification programs for accurate measures of their effect and the ability to address concerns as they arise. This review highlights the history, effect, concerns, and future directions of folic acid food fortification programs.
publisher MDPI
publishDate 2011
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257747/
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