Folic Acid Food Fortification—Its History, Effect, Concerns, and Future Directions
Periconceptional intake of folic acid is known to reduce a woman’s risk of having an infant affected by a neural tube birth defect (NTD). National programs to mandate fortification of food with folic acid have reduced the prevalence of NTDs worldwide. Uncertainty surrounding possible unintended cons...
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pubmed-32577472012-01-17 Folic Acid Food Fortification—Its History, Effect, Concerns, and Future Directions Crider, Krista S. Bailey, Lynn B. Berry, Robert J. Review Periconceptional intake of folic acid is known to reduce a woman’s risk of having an infant affected by a neural tube birth defect (NTD). National programs to mandate fortification of food with folic acid have reduced the prevalence of NTDs worldwide. Uncertainty surrounding possible unintended consequences has led to concerns about higher folic acid intake and food fortification programs. This uncertainty emphasizes the need to continually monitor fortification programs for accurate measures of their effect and the ability to address concerns as they arise. This review highlights the history, effect, concerns, and future directions of folic acid food fortification programs. MDPI 2011-03-15 /pmc/articles/PMC3257747/ /pubmed/22254102 http://dx.doi.org/10.3390/nu3030370 Text en © 2011 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
repository_type |
Open Access Journal |
institution_category |
Foreign Institution |
institution |
US National Center for Biotechnology Information |
building |
NCBI PubMed |
collection |
Online Access |
language |
English |
format |
Online |
author |
Crider, Krista S. Bailey, Lynn B. Berry, Robert J. |
spellingShingle |
Crider, Krista S. Bailey, Lynn B. Berry, Robert J. Folic Acid Food Fortification—Its History, Effect, Concerns, and Future Directions |
author_facet |
Crider, Krista S. Bailey, Lynn B. Berry, Robert J. |
author_sort |
Crider, Krista S. |
title |
Folic Acid Food Fortification—Its History, Effect, Concerns, and Future Directions |
title_short |
Folic Acid Food Fortification—Its History, Effect, Concerns, and Future Directions |
title_full |
Folic Acid Food Fortification—Its History, Effect, Concerns, and Future Directions |
title_fullStr |
Folic Acid Food Fortification—Its History, Effect, Concerns, and Future Directions |
title_full_unstemmed |
Folic Acid Food Fortification—Its History, Effect, Concerns, and Future Directions |
title_sort |
folic acid food fortification—its history, effect, concerns, and future directions |
description |
Periconceptional intake of folic acid is known to reduce a woman’s risk of having an infant affected by a neural tube birth defect (NTD). National programs to mandate fortification of food with folic acid have reduced the prevalence of NTDs worldwide. Uncertainty surrounding possible unintended consequences has led to concerns about higher folic acid intake and food fortification programs. This uncertainty emphasizes the need to continually monitor fortification programs for accurate measures of their effect and the ability to address concerns as they arise. This review highlights the history, effect, concerns, and future directions of folic acid food fortification programs. |
publisher |
MDPI |
publishDate |
2011 |
url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257747/ |
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1611499814397149184 |