Calpains Mediate Integrin Attachment Complex Maintenance of Adult Muscle in Caenorhabditis elegans

Two components of integrin containing attachment complexes, UNC-97/PINCH and UNC-112/MIG-2/Kindlin-2, were recently identified as negative regulators of muscle protein degradation and as having decreased mRNA levels in response to spaceflight. Integrin complexes transmit force between the inside and...

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Bibliographic Details
Main Authors: Etheridge, Timothy, Oczypok, Elizabeth A., Lehmann, Susann, Fields, Brandon D., Shephard, Freya, Jacobson, Lewis A., Szewczyk, Nathaniel J.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257289/