Modulation of the Pentose Phosphate Pathway Induces Endodermal Differentiation in Embryonic Stem Cells

Embryonic stem (ES) cells can differentiate in vitro into a variety of cell types. Efforts to produce endodermal cell derivatives, including lung, liver and pancreas, have been met with modest success. Understanding how the endoderm originates from ES cells is the first step to generate specific cel...

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Bibliographic Details
Main Authors: Manganelli, Genesia, Fico, Annalisa, Masullo, Ugo, Pizzolongo, Fabiana, Cimmino, Amelia, Filosa, Stefania
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257253/