TCR cross-reactivity and allorecognition: new insights into the immunogenetics of allorecognition
Alloreactive T cells are core mediators of graft rejection and are a potent barrier to transplantation tolerance. It was previously unclear how T cells educated in the recipient thymus could recognize allogeneic HLA molecules. Recently it was shown that both naïve and memory CD4+ and CD8+ T cells ar...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Springer-Verlag
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253994/ |