B-Cell-Activating Factor and Autoimmune Myasthenia Gravis
BAFF is a potent B-cell survival factor, and it plays an essential role in B-cell homeostasis and B-cell function in the periphery. Both normal and autoreactive B cells are BAFF dependent; however, excess BAFF promotes the survival, growth, and maturation of autoreactive B cells. When overexpressed,...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
SAGE-Hindawi Access to Research
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251912/ |