γ-Tubulin 2 Nucleates Microtubules and Is Downregulated in Mouse Early Embryogenesis

γ-Tubulin is the key protein for microtubule nucleation. Duplication of the γ-tubulin gene occurred several times during evolution, and in mammals γ-tubulin genes encode proteins which share ∼97% sequence identity. Previous analysis of Tubg1 and Tubg2 knock-out mice has suggested that γ-tubulins are...

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Bibliographic Details
Main Authors: Vinopal, Stanislav, Černohorská, Markéta, Sulimenko, Vadym, Sulimenko, Tetyana, Vosecká, Věra, Flemr, Matyáš, Dráberová, Eduarda, Dráber, Pavel
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250491/