Laminin 511 partners with laminin 332 to mediate directional migration of Madin–Darby canine kidney epithelial cells

Laminin 511 partners with laminin 332 to mediate directional migration of Madin–Darby canine kidney epithelial cells

Directional migration of MDCK cells is regulated by the ratio of the deposited basement membrane proteins laminin-511 and laminin-332. Knockdown of laminin-511 or its receptor integrin α3 inhibits directional migration and destabilizes cell–cell contacts, disturbing the polarization machinery.

Bibliographic Details
Main Authors: Greciano, Patricia G., Moyano, Jose V., Buschmann, Mary M., Tang, Jun, Lu, Yue, Rudnicki, Jean, Manninen, Aki, Matlin, Karl S.
Format: Online
Language:English
Published: The American Society for Cell Biology 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248892/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248892/

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