Recovering Protein-Protein and Domain-Domain Interactions from Aggregation of IP-MS Proteomics of Coregulator Complexes

Coregulator proteins (CoRegs) are part of multi-protein complexes that transiently assemble with transcription factors and chromatin modifiers to regulate gene expression. In this study we analyzed data from 3,290 immuno-precipitations (IP) followed by mass spectrometry (MS) applied to human cell li...

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Bibliographic Details
Main Authors: Mazloom, Amin R., Dannenfelser, Ruth, Clark, Neil R., Grigoryan, Arsen V., Linder, Kathryn M., Cardozo, Timothy J., Bond, Julia C., Boran, Aislyn D. W., Iyengar, Ravi, Malovannaya, Anna, Lanz, Rainer B., Ma'ayan, Avi
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248428/