The direct Myc target Pim3 cooperates with other Pim kinases in supporting viability of Myc-induced B-cell lymphomas
The Pim kinases are weak oncogenes. However, when co-expressed with a strong oncogene, such as c-Myc, Pim kinases potentiate the oncogenic effect resulting in an acceleration of tumorigenesis. In this study we show that the least studied Pim kinase, Pim-3, is encoded by a gene directly regulated by...
Main Authors: | , , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Impact Journals LLC
2011
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248204/ |