A Chemical Biology Approach to Developing STAT Inhibitors: Molecular Strategies for Accelerating Clinical Translation
STAT transcription factors transduce signals from the cell surface to the nucleus, where they regulate the expression of genes that control proliferation, survival, self-renewal, and other critical cellular functions. Under normal physiological conditions, the activation of STATs is tightly regulate...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Impact Journals LLC
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248200/ |