No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis

The Warburg effect describes the circumstance that tumor cells preferentially use glycolysis rather than oxidative phosphorylation for energy production. It has been reported that this metabolic reconfiguration originates from a switch in the expression of alternative splice forms (PKM1 and PKM2) of...

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Bibliographic Details
Main Authors: Bluemlein, Katharina, Grüning, Nana-Maria, Feichtinger, René G., Lehrach, Hans, Kofler, Barbara, Ralser, Markus
Format: Online
Language:English
Published: Impact Journals LLC 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248187/