Further Support to the Uncoupling-to-Survive Theory: The Genetic Variation of Human UCP Genes Is Associated with Longevity
In humans Uncoupling Proteins (UCPs) are a group of five mitochondrial inner membrane transporters with variable tissue expression, which seem to function as regulators of energy homeostasis and antioxidants. In particular, these proteins uncouple respiration from ATP production, allowing stored ene...
Main Authors: | Rose, Giuseppina, Crocco, Paolina, De Rango, Francesco, Montesanto, Alberto, Passarino, Giuseppe |
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Format: | Online |
Language: | English |
Published: |
Public Library of Science
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246500/ |
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