Inhibition of endothelial- and neuronal-type, but not inducible-type, nitric oxide synthase by the oxidized cholesterol metabolite secosterol aldehyde: Implications for vascular and neurodegenerative diseases
The cholesterol ozonolysis products secosterol-A and its aldolization product secosterol-B were recently detected in human atherosclerotic tissues and brain specimens, and have been postulated to play pivotal roles in the pathogenesis of atherosclerosis and neurodegenerative diseases. We examined se...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
the Society for Free Radical Research Japan
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246188/ |