Hyperactive EGF receptor, Jaks and Stat3 signaling promote enhanced colony-forming ability, motility and migration of cisplatin-resistant ovarian cancer cells

Hyperactive EGF receptor, Jaks and Stat3 signaling promote enhanced colony-forming ability, motility and migration of cisplatin-resistant ovarian cancer cells

We present evidence that the cisplatin-resistant human ovarian cancer lines, A2780S/CP1 (S/CP1), A2780S/CP3 (S/CP3), and A2780S/CP5 (S/CP5), derived by subjecting the sensitive A2780S ovarian cancer line to multiple rounds of cisplatin treatments followed by recovery and are resistant to 1, 3, and 5...

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Bibliographic Details
Main Authors: Yue, Peibin, Zhang, Xiaolei, Paladino, David, Sengupta, Bhaswati, Ahmad, Sarfraz, Holloway, Robert W., Ingersoll, Susan B., Turkson, James
Format: Online
Language:English
Published: 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245777/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245777/

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